The mRNA Expression of Different Muscle Fibre Types in Denervated Rat Musculus Cricoarytenoideus Posterior
- VernacularTitle:去神经支配后大鼠环杓后肌不同类型肌纤维的mRNA表达
- Author:
Mingrong NIE
;
Siyi ZHANG
;
Pingjiang GE
;
Shaofeng LIU
;
Shaohua CHEN
;
Xiaoli SHENG
- Publication Type:Journal Article
- Keywords:
Denervation;
Posterior cricoarytenoid muscle;
Reverse transcriptase polymerase chain reaction
- From:
Journal of Audiology and Speech Pathology
2004;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of the mRNA of muscle fibre types in the denervated post cricoarytenoid(PCA)muscle of rat.Methods Unilateral recurrent laryngeal nerve of eight rats were removed.Eight rats were used as controls.The mRNA expression of heavy chain myosin of PCA muscle fibre subtypes was measured with real-time quantitative RT-PCR in control rats and denervated rats 40 days after denervation.Results Compared to the control group,there were no significantly differences in mRNA expression of each muscle subtype between two groups.The ratio of MyHC type I to IIB was increased significantly(P=0.018).Conclusion The increased ratio of MyHC subtype I to IIB suggests the decreased contraction power of denervated PCA muscle.
