Effect of ~(60)Co-?-Rays on the Active Component of Radix Paeoniae Rubra
- VernacularTitle:~(60)钴-?射线对赤芍药材有效成分的影响
- Author:
Dongmei WU
- Publication Type:Journal Article
- Keywords:
Radix Paeoniae Rubra;
60Co-?-rays;
Paeoniflorin;
Content;
Effect
- From:
China Pharmacy
2005;0(24):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To study the change of the active components in Radix Paeoniae Rubra before and after the radiation of 60Co-?-rays.METHODS: The content of paeoniflorin in Radix Paeoniae Rubra before and after the radiation of 60Co-?-rays was determined by HPLC on Spherigel ODS C18(150 mm?4.6 mm,5 ?m) chromatographic column.The mobile phase consisted of methanol-water(gradient elution) with the detection wavelength set at 260.5 nm.RESULTS: The content of paeoniflorin in Radix Paeoniae Rubra dropped by nearly 20% after the radiation of 60Co-?-rays.CONCLUSION: The effect of the radiation of 60Co?-rays on the active component should be taken into consideration in treating the Chinese drugs preparation of Radix Paeoniae Rubra.
