Effect of topical corticosteroids on expression of eotaxin in nasal polyps
- VernacularTitle:局部应用糖皮质激素对鼻息肉组织中Eotaxin蛋白的影响
- Author:
Xiumin REN
;
Yan ZHANG
;
Naichao DUAN
;
Yanzhong YANG
- Publication Type:Journal Article
- Keywords:
Nasal Polyps;
Chemotactic Factors,Eosinophil;
Eosinophils;
Glucocorticoids
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2006;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To observe the effect s of local corticosteroids on the expression of Eotaxin in nasal polyps and the mechanism of corticosteroids in the treatment of nasal polyps.METHODS The SP immunohistochemical method was used to detect the expression of Eotaxin in nasal polyps before and after treatment with corticosteroids.RESULTS The protein level of eotaxin significantly increased in the nasal polyps compared to the control tissues(P