Tumor stem cells and glioma initiating cells
- VernacularTitle:肿瘤干细胞与胶质瘤细胞起源
- Author:
Ping LI
;
Xueyun ZHONG
- Publication Type:Journal Article
- Keywords:
Tumor stem cells;
Glioma;
Brain tumor stem cells;
Cell differentiation
- From:
Chinese Journal of Pathophysiology
2000;0(08):-
- CountryChina
- Language:Chinese
-
Abstract:
The tumor stem cell theory supposed that tumor stem cells are the origin of tumor abnormal proliferation,invasion,metastasis,drug resistance and recurrence.As the theory is put forward,it redefines the functions of classic stem cells in tumorigenesis.It is a great event for recent studies on glioma initiating cells as brain tumor stem cells were identified and isolated successfully.A lot of evidence from experiments in vivo and in vitro demonstrates that brain tumor stem cells might play an important role in glioma tumorigenesis.In this review,we discuss the relationship between tumor stem cells and tumorigenesis,and the research on the correlation between brain tumor stem cells and glioma genesis.
