Optimization of the Technology of Extracting Total Flavonoids from Sophora Japonica by Response Surface Methodology
- VernacularTitle:效应面设计法优化槐花中总黄酮提取工艺
- Author:
Xinsheng PENG
;
Siting LIANG
;
Shenglan SHEN
;
Shaotang MAI
;
Yanhong HUANG
- Publication Type:Journal Article
- Keywords:
Response surface;
Sophora japonica;
Total flavonoids;
Extracting technology
- From:
China Pharmacy
2005;0(21):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To optimize the technology of extracting total flavonoids from Sophora japonica.METHODS: The extracting technology of total flavonoids (from Sophora japonica) was optimized by response surface methodology(RSM) with ethanol concentration,solid-solvent ratio,extracting temperature,extracting time and extracting times as factors and the yield of total flavonoids as index.RESULTS: The optimal parameters were determined as follows: the ethanol concentration was 60%;the solid-solvent ratio was 1∶10;the extracting was conducted for 1 time(90 min) at 90 ℃.CONCLUSION:The optimized extraction technology was simple and stable and which serves as references for industrial large scale production.
