Application of ~(125)I seeds brachytherapy in advanced head and neck malignant tumor combined with surgery
- VernacularTitle:外科手术联合放射性粒子~(125)I植入治疗晚期头颈部恶性肿瘤
- Author:
Bo DU
;
Yusheng WANG
;
Yan ZHANG
;
Baodong DU
- Publication Type:Journal Article
- Keywords:
Head and Neck Neoplasms;
Radiolherapy;
Surgical Procedures,Operative
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To evaluate the effectiveness of ~(125)I seeds brachytherapy in advanced head and neck malignant tumor.METHODS Twelve patients with post-radiotherapy recurred laryngeal cancer with bilateral cervical lymph node metastasis, tongue cancer with bilateral cervical lymph node metastasis or recurred maxillary sinus cancer and so on were operated radically,and ~(125)I seeds were implanted in wound area during operation.RESULTS With a follow-up of 24 to 32 months,no tumor recurred in 11 patients,and only one patient with tongue cancer recurred at 6 month after operation.No local infection, acute radioactive lesion,vessel broken or seeds migration happened.CONCLUSION The ~(125)I brachytherapy can be used as one of the comprehensive treatment method in advanced head and neck malignant tumors,especially in the recurred tumors after operation or radiotherapy or in the cancer which can not be radically removed.It's also an effective method to improve local control in the subset of patients with doubtful positive margins.
