Characteristics of Myocardial Deformation and Rotation in Subjects With Diastolic Dysfunction Without Diastolic Heart Failure.
10.4070/kcj.2009.39.12.532
- Author:
Hee Sang JANG
1
;
Jae Hoon KIM
;
Byung Seok BAE
;
Seung Min SHIN
;
Ki Ju KIM
;
Jung Gil PARK
;
Hyun Jae KANG
;
Bong Ryeol LEE
;
Byung Chun JUNG
Author Information
1. Department of Cardiology, Fatima General Hospital, Daegu, Korea. Augustjbc@yahoo.co.kr
- Publication Type:Original Article
- Keywords:
Heart failure, diastolic;
E/E' Ratio;
Echocardiography, Doppler
- MeSH:
Echocardiography, Doppler;
Heart;
Heart Failure;
Heart Failure, Diastolic;
Sprains and Strains;
Stroke Volume;
Track and Field
- From:Korean Circulation Journal
2009;39(12):532-537
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND AND OBJECTIVES: There have been very few pathophysiologic studies on isolated diastolic dysfunction. We hypothesized that the characteristics of isolated diastolic dysfunction would be located, on the clinical continuum, between those of a normal heart and diastolic heart failure. SUBJECTS AND METHODS: We enrolled 102 subjects who had no history of overt symptoms of heart failure and who had a left ventricular ejection fraction of more than 50%. They were examined for myocardial deformation and rotation using the two-dimensional speckle tracking image (2D-STI) technique. RESULTS: The circumferential strains and radial strain at the apical level (RS(apex)) were related to the ratio of the transmitral early peak velocity over the early diastolic mitral annulus velocity (E/E'). After adjustment for age, the RS(apex) showed a positive relationship with the E/E' ratio; whereas, the circumferential strains did not. Instead, the circumferential strains demonstrated a significant correlation with age. Basal rotation and left ventricular (LV) torsion were also related to age, but had no relationship with the E/E' ratio. However, as the E/E' ratio value increased, systolic mitral annular velocity decreased. CONCLUSION: Except for the RS(apex), LV myocardial deformation and rotation did not vary with the degree of E/E' ratio elevation when there was no associated diastolic heart failure. Additionally, in clinical situations such as isolated diastolic dysfunction, the advancement of age has a relatively greater influence on characteristics of LV myocardial deformation and rotation rather than on the E/E' ratio.
