Stability of Cefoperazone Sodium /Tazobactam Sodium for Injections in Fructose-contained Sodium Chloride Injection or Invertose Injection
- VernacularTitle:头孢哌酮/他唑巴坦钠在含果糖氯化钠注射液和转化糖注射液中的稳定性考察
- Author:
Xuesong LI
;
Long YANG
;
Bin QIAN
;
Xiaojun LI
;
Yuanzhi YAN
;
Jiaai YANG
- Publication Type:Journal Article
- Keywords:
Cefoperazone Sodium /Tazobactam Sodium;
Fructose injection;
Invertose injection;
Mixing;
Stability
- From:
China Pharmacy
2005;0(20):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the stability of Cefoperazone Sodium /Tazobactam Sodium in Fructose-contained 0.9% sodium chloride injection or Invertose Injection.METHODS:The contents of Cefoperazone Sodium /Tazobactam Sodium within 6 hours after mixing with Fructose-contained 0.9% sodium chloride injection or Invertose Injection were determined by HPLC,meanwhile the changes in the appearances and the pH values were observed.RESULTS:The contents of Cefoperazone Sodium and Tazobactam Sodium in Fructose-contained 0.9% sodium chloride injection or Invertose Injection were stable within 6 hours,and the mixed solutions were clear and their pH values were stable on the whole.CONCLUSION:Cefoperazone Sodium /Tazobactam Sodium can de mixed with Fructose-contained 0.9% sodium chloride injection or Invertose Injection for clinical use.
