Effects of Piracetam on Superoxide Dismutase Activity and Malonaldehyde Content in Brain Tissues of D-galactose-induced Aging Rats
- VernacularTitle:吡拉西坦对D-半乳糖致衰老模型大鼠脑组织超氧化物歧化酶活性和丙二醛含量的影响
- Author:
Zhanxiong XIE
;
Jianwei WU
;
Tiesong WU
;
Donghong QIU
;
Xiulian XIAO
- Publication Type:Journal Article
- Keywords:
Piracetam;
Aging;
Rat;
Superoxide dismutase;
Malonaldehyde
- From:
China Pharmacy
2005;0(19):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To explore the effects of piracetam on superoxide dismutase(SOD) activity and malonaldehyde(MDA) content in brain tissues of D-galactose-induced ageing rats.METHODS: 30 SD rats were randomized to one of the 3 groups: blank control group(NS),model group(D-galactose+NS) and piracetam group(D-galactose+piracetam 432 mg?kg-1?d-1).All the rats were put to death at 90 days after medication,and the SOD activity and MDA content in brain tissues were determined.RESULTS: As compared with the blank control,the SOD activity decreased(P
