Effects of Tanreqing Injection on Immune Factors and Clinical Outcome in Patients with Ventilator Associated Pneumonia
- VernacularTitle:痰热清注射液对呼吸机相关性肺炎患者免疫因子和临床预后的影响研究
- Author:
Yingxi YU
;
Jinglun LIU
- Publication Type:Journal Article
- Keywords:
Tanreqing injection;
Ventilator associated pneumonia;
Immune factor;
Clinical prognosis
- From:
China Pharmacy
2005;0(18):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the effects of Tanreqing injection on the immune factors and clinical outcome in patients with ventilator associated pneumonia(VAP).METHODS:155 patients with VAP were randomly divided into trial group and control group.Serum levels of CRP,IL-6 and TNF-? were determined at 0,1,3,5 and 7 days after treatment.The chest X-ray results at 0 and 3 days after treatment were compared.The mechanical ventilation(MV)time and the successful rate of weaning from mechanical ventilation and the mortality rate were recorded.RESULTS:The serum levels of CRP,IL-6 and TNF-? in all 155 VAP patients were significantly higher than normal levels,at 5 days,serum levels of IL-6 and TNF-? in the trial group began to decrease significantly as compared with the control group(P
