Efficacy and Safety of Different Density of Levobupivacaine for Combined Spinal and Epidural Anesthesia in Elder Patients
- VernacularTitle:不同比重左旋布比卡因在高龄患者腰麻-硬膜外联合麻醉中的比较研究
- Author:
Hui XU
- Publication Type:Journal Article
- Keywords:
Density;
Levobupivacaine;
Eld;
Combined spinal and epidural anesthesia
- From:
China Pharmacy
2005;0(17):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To compare the efficacy and safety of different density of Levobupivacaine for combined spinal and epidural anesthesia (CSEA) in elder patients. METHODS: Sixty elder patients undergoing transurethral prostatectomy (TURP) were randomly assigned to 1 of the 3 groups: Group Ⅰ(n=20,hypobaric group) received 0.75% Levobupivacaine 1 mL+ 0.5 mL 0.9% Sodium Chloride Injection,Group Ⅱ(n=20,isobaric group) received 0.75% Levobupivacaine 1 mL+0.5 mL cerebrospinal fluid,and Group Ⅲ(n=20,hyperbaric group) received 1 mL 0.75% Levobupivacaine+0.5 mL 10% Glucose. RESULTS: All the 3 groups achieved satisfactory anesthetic efficacy. The incidences of hypotension,nausea,vomiting and shivering were significantly lower in Group Ⅲ than in other two groups (Group Ⅰ and Group Ⅱ)(P