Clinical Observation on 50 Cases of Schizophrenia Treated by Jieyu Huatan Anshen Formula Combined with risperidone
- VernacularTitle:解郁化痰安神方合并利培酮治疗精神分裂症50例临床观察
- Author:
Renyi ZHOU
- Publication Type:Journal Article
- Keywords:
Schizophrenia;
Jieyu Huatan Anshen Formula(Formula for relieving stagnation,dissolving phlegm and calming the mind);
Risperidone
- From:
Journal of Traditional Chinese Medicine
1993;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To compare the effect and safety of Jieyu Huatan Anshen Formule(Formula for relieving stagnation,dissolving phlegm and calming the mind) combined with risperidone and risperidone used singly in the treatment of schizophrenia.Methods Totally the 100 schizophrenia patients were randomized into a control group(n=50),treated with risperidone,and a study group(n=50),treated by Jieyu Huatan Anshen Formula combined with the half dosage of risperidone.The observation lasted 8 weeks.The therapeutic effect and safety were evaluated by the positive and negative syndrome scale(PANSS),clinical global impression(CGI),and treatment emergent symptom scale(TESS).Results After treatment,the PANSS total scores and the factor scores of both groups were significantly decreased(P0.05).The in-group comparison of CGI effect showed a significant difference(P0.05).The incidence of side effect of the study group and the control control group was 18% and 52% respectively,there exsisted a significant difference(P
