Determination of the Dissolution of Qingyangshen Dispersible Tablets
- VernacularTitle:青阳参分散片溶出度测定
- Author:
Weilin LI
;
Jun HE
;
Yixin QIAN
- Publication Type:Journal Article
- Keywords:
Qingyangshen dispersible tablets;
Qingyangshengenin;
Dissolution;
HPLC
- From:
China Pharmacy
2005;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish a method for the determination of the dissolution of Qingyangshen dispersible tablets so as to provide method and parameters for quality control of this kind of tablets.METHODS:With water as dissolution medium in a rotating speed of 100 r?min-1,the dissolution of Qingyangshen dispersible tablets was determined by HPLC at a wavelength of 259 nm.RESULTS:Similar dissolution rates were obtained for 3 batches of Qingyangshen dispersible tablets,with accumulative dissolution rates of all samples at 45 minutes reached above 90%,and a good reproducibility was noted.CONCLUSION:The quality of Qingyangshen dispersible tablets is up to the standard stated in Chinese Pharmacopoeia(2005 Edition).
