Stability of Levocarnitine Injections from Two Manufactories in 3 Different Dissolvants
- VernacularTitle:两厂家左卡尼汀注射液在3种溶媒中的稳定性考察
- Author:
Yajing LI
;
Chen WANG
- Publication Type:Journal Article
- Keywords:
Levocarnitine injection;
HPLC;
Combination;
Stability
- From:
China Pharmacy
2001;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To provide reference for clinical rational drug use.METHODS:The content of Levocarnitine Injection from two manufactories in 3 different dissolvants(5%Glucose,0.9%Sodium Chloride Injection,and Fructose Injection) within 6 h was determined by HPLC.The change of microparticle was measured by light blockage method in accordance with China Pharmacopeia(2005 edition),and the appearance and pH of the mixtures were observed as well.RESULTS: The changes in appearance,turbidance,pH value,content and microparticle were not significant.CONCLUSION: Levocarnitine Injections from two manufactories were stable within 6 h after mixing with 3 different dissolvants(5%Glucose, 0.9%Sodium Chloride Injection,and Fructose Injection).
