Effects of deep-frozen treatment on the immune response of bone-patellar tendon-bone xenograft rejection
- VernacularTitle:深低温处理对异种骨-髌腱-骨移植排斥反应的影响
- Author:
Kejia CHEN
;
Dejiu WANG
;
Yabin JIANG
;
Yaoying ZENG
- Publication Type:Journal Article
- Keywords:
Bone-patellar tendon-bone;
Xenograft;
Rejection;
Interleukin-2;
Anterior cruciate ligament
- From:
Chinese Journal of Pathophysiology
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the effects of deep-frozen treatment on the immune response of bone-patellar tendon-bone(BPB) xenograft rejection.METHODS: A muscle pocket model was used to study the immune response of rat to deep-frozen treated BPB xenograft from guinea pig,autograft and fresh xenograft served as controls.The expression of T-cell surface activation antigen CD25 in the peripheral blood and the morphological changes of the implants were used to measure the immune response.RESULTS: The expression of CD25 in CD4+,CD8+ cells greatly increased 3 d after fresh BPB xenograft,the obvious difference to that of autograft(P