Effect of Lipo PGE1 Mecobalamine and Ginkgo-dipyidamolun on Treatment of Diabetic Peripheral Neuropathy
- VernacularTitle:弥可葆、前列地尔和银杏达莫联合用药治疗糖尿病周围神经病变的疗效观察
- Author:
Hongmei LI
;
Shuirong LU
;
Shuling LI
- Publication Type:Journal Article
- Keywords:
Lipo PGE1;
Meobalamine;
Ginkgo-dipyidamolum;
Diabetic Peripheral Neuropathy
- From:
Chinese Journal of Prevention and Control of Chronic Diseases
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Lipo PGE1 and Mecobalamine and Ginkgo-dipyidamolun in the treatment of dia-betic peripheral neuropathy. Methods 60 Patients with diabetic peripheral neuropathy were divided randomly into two groups; the control group (30 cases) and the treatment group (30 cases). The patients of the treatment group were given with Lipo PGE1 100 ?g dissolved in 0.9% normal saline solution 100ml once a day intravenously, and given mecobalamine 500 ?g once a day intramuscular, and given Ginko-dipyidamolum injection 20ml dissolved in 0.9% normal saline solution 250ml once a day intravenously; and in the control group were only given with mecobalamine 500?g once a day intramuscular. Nerve conduction velocity (MNCV and SNCV) in two groups of patients was observed after 14 days treatment. Results After treatment for 14 days, the subjective symptoms and signs were significantly improved with a total effective rate of 86.7% in the treatment group versus 56.7% in the control group. Compared with the control group, the total effective rates of treatment group was significantly higher (P