Effect of Astragalus Injection as an Adjunctive Therapy on the Biology in Patients with Schizophrenia and Its Clinical Efficacy
- VernacularTitle:黄芪注射液辅助治疗对慢性精神分裂症患者生物学的影响及疗效观察
- Author:
Ruiguo QUAN
;
Bingquan LI
;
Liqin LI
;
Dongming WANG
;
Peiyi SONG
;
Furen CHEN
- Publication Type:Journal Article
- Keywords:
Astragalus injection;
Chronic schizophrenia;
Biology;
Clinical efficacy;
Adjunctive therapy
- From:
China Pharmacy
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the effect of Astragalus injection as an adjunctive therapy on the biology in patients with schizophrenia and its clinical efficacy. METHODS: A total of 100 patients with schizophrenia were randomly assigned to trial group(n=50) or control group(n=50). The trial group received routine antipsychotic drugs plus Astragalus injection (40 mL?d-1, iv gtt) for 7 days, and the control group received antipsychotic drugs alone without addition of traditional Chinese medicine for 7 days. All the patients received for a total of 4 courses of treatment. Besides, both groups received additional benzodiazepine but not other hipnotics. RESULTS: After treatment, there were significant differences between the trial group and the control group in ECG QTc duration, sugar level, therapeutic efficacy, PANSS scores (total score and the sub-item scores) and adverse reactions etc(P
