Simultaneous Determination of the Contents of Salicylic Acid and Nitrofural in Fu-La Pastes by UV Spectrophotometry
- VernacularTitle:紫外分光光度法同时测定呋喃西林拉氏糊中水杨酸和呋喃西林的含量
- Author:
Yanpeng WANG
;
Qingyuan HOU
;
Ting ZHANG
- Publication Type:Journal Article
- Keywords:
UV spectrophotometry;
Salicylic acid;
Nitrofural;
Content
- From:
China Pharmacy
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To establish a method for the simultaneous determination of the contents of salicylic acid and nitrofural in Fu-La pastes.METHODS: A dual-wavelength spectrophotometry was adopted for the determination of the contents of salicylic acid and nitrofural with water used as solvent.The content of salicylic acid was determined with the detective wavelength set at 296.6 nm and the reference wavelength set at 314.4 nm.The content of the nitrofural was determined directly with the detective wavelength set at 375.0 nm.RESULTS: The linear ranges of salicylic acid and nitrofural were 10.77～43.08 ?g?mL-1(r=0.999 0) and 2.58～10.32 ?g?mL-1(r=1.000 0),respectively;and their average recovery rates were 99.55%(RSD=0.47%) and 100.03%(RSD=0.80%),respectively.CONCLUSION: The method is simple,rapid and accurate,and suitable for the quality control of Fu-La pastes.
