Compatible Stability of Gatifloxacin for Injection in Combination with Cefathiamidine for Injection
- VernacularTitle:注射用加替沙星与头孢硫脒的配伍稳定性考察
- Author:
Ruiqin LIU
;
Jizhang YANG
- Publication Type:Journal Article
- Keywords:
Gatifloxacin;
Cefathiamidine;
Compatibility;
Stability;
Ultraviolet spectrophotometry
- From:
China Pharmacy
1991;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To study the compatible stability of gatifloxacin for injection in combination with cefathiamidine for injection in 0.9% sodium chloride injection or in 5% glucose injection.METHODS: Changes in appearance and pH value of the mixture of gatifloxcation and cefathiamidine within 8 hours after mixing were respectively observed and determined under room temperature(20?1)℃,and the contents were determined by dual ultraviolet spectrophotometry.RESULTS: The appearance,pH value and contents as well as the ultraviolet absorption peak shape of the mixture showed no significant change within 8 hours after mixing in 0.9% sodium chloride injection or 5% glucose injection.CONCLUSION: Gatifloxacin for injection can be mixed with cefathiamidine for injection in 0.9% sodium chloride injection or 5% glucose injection to use.
