Impaired glucose tolerance,angiopathy and advanced glycation end products
- VernacularTitle:糖耐量异常与血管病变及糖基化终产物
- Author:
Yashi ZHAN
;
Lie FENG
- Publication Type:Journal Article
- Keywords:
Impaired glucose tolerance;
Angiopathy;
Glycosylation end products,advanced;
Diabetes mellitus
- From:
Chinese Journal of Pathophysiology
1986;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
The definition of impaired glucose tolerance (IGT) was first introduced by the National Diabetes Data Group at 1979. Recently the morbidity rate of IGT is soaring. About 10%-15% of patients with IGT will progress to type 2 diabetes mellitus (T2DM) which is approximately more than 100 times comparing with normal glucose tolerance people. Angiopathy can be detected in 40% patients with newly diagnosed IGT. Advanced glycation end products (AGEs) are closely related to angiopathy. Meanwhile there is some connection between IGT and AGEs. In this review, the relationship between IGT, agiopathy and AGEs is discussed.
