Optimization of the Extraction Process of Total Flavonoids from Pueraria lobata by Uniform Design
- VernacularTitle:均匀设计法优选葛根总黄酮提取工艺
- Author:
Dongqing ZHU
;
Qingxin KONG
- Publication Type:Journal Article
- Keywords:
Ultrasonic method;
Extraction;
Pueraria lobata;
Total flavonoids;
Extraction condition;
Homogeneous design
- From:
China Pharmacy
1991;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To optimize the extraction conditions of total flavones from Pueraria Lobata by ultrasonic method.METHODS:The uniform design method was applied to investigate the effects of alcohol content,the quantity of solvent,extraction time,extraction temperature and the extraction times on the result of extraction.The content of total flavone of Pueraria Lobata was determined by ultraviolet-visible spectrophotometry.The extraction conditions were optimized with the extraction yield and the mass fraction of total flavone of Pueraria lobata in the extract as indexes.RESULTS:The optimal extraction conditions were as follows:extracting with 75% alcohol(20 mL?g-1) for 40 min(extraction time) at 68 ℃(extraction temperature) for a total of 5 times.CONCLUSION:The extraction process is reasonable and feasible and it provides theoretic basis for the industrialized production.
