Content Determination of Main Components in Racanisodamine Hydrochloride Injection by HPLC
- VernacularTitle:HPLC法测定盐酸消旋山莨菪碱注射液中主药的含量
- Author:
Yan DING
- Publication Type:Journal Article
- Keywords:
Racanisodamine hydrochloride;
HPLC;
Content determination
- From:
China Pharmacy
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To establish an HPLC method for the determination of the content of main components in racanisodamine hydrochloride(RH) injection.METHODS: The determination was performed on Phenomenex Luna C18 column with methanol-0.02% triethylamine(50∶50) used as mobile phase at a flow rate of 1.0 mL?min-1.The detecting wavelength was set at 220 nm;the column temperature was set at room temperature and the sample size was 20 ?L.RESULTS: The linear range of RH was 0.053～0.371 ?g?mL-1(r=0.999 9) and the average recover was 101.20%(RSD=0.23%,n=6).CONCLUSIONS: The method is proved to be simple,rapid,accurate and applicable for the determination of the content of RH in RH injection.
