Clinical Observation on the Cough-relieving Efficacy of Guaifenesin-Pseudoephedrine Hydrochloride-Codeine Phosphate Oral Solution
- VernacularTitle:愈酚伪麻待因口服液镇咳、祛痰临床研究
- Author:
Sijing LU
;
Zhong LIU
;
Yu LIU
;
Xue JIAO
- Publication Type:Journal Article
- Keywords:
Guaifenesin pseudoephedrine hydrochloride-odeine phosphate oral solution;
Ambroxol hydrochloride oral solution;
Efficacy;
Safety
- From:
China Pharmacy
1991;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the cough-relieving and sputum-eliminating efficacy and safety of Guaifenesin Pseudoephedrine Hydrochloride-Codeine Phosphate Oral Solution.METHODS:By a randomized control study,a total of 60 patients characterized by nonproductive cough andlittle sputum were randomly assigned to receive Guaifenesin Pseudoephedrine Hydrochloride-Codeine Phosphate Oral Solution(Trial Group)or Ambroxol Hydrochloride Oral Solution(Control Group)l0 mL tid for 5～7 d.RESULTS:Both groups had a significant improvement in symptoms including cough and expectoration after treatment(P0.05).CONCLUSION:Guaifenesin Pseudoephedrine Hydrochloride-Codeine Phosphate Oral Solution is more effective in relieving cough than Ambroxol Oral Solution,and it has certain effect in eliminating phlegm.In addition,it is safe and has little adverse reaction.
