Quality Standard of Xiaochuan Oral Solution
- VernacularTitle:哮喘口服溶液的质量标准研究
- Author:
Li DENG
;
Cai LIN
;
Bin HU
;
Hongjun HE
- Publication Type:Journal Article
- Keywords:
Xiaochuan oral solution;
Guaifenesin;
Ephedrine hydrochloride;
Aminophlline;
HPLC;
Qnality control
- From:
China Pharmacy
1991;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To establish xiaochuan oral oral solution quality control method.METHODS: Three kinds of main components' contents in xiaochuan oral solution were determined by HPLC.RESULTS: The prepared oral solution was brown liquid,with identification and tests all up to the standards specified in Chinese Pharmacopeia(2005 edition).The linear ranges of guaifenesin,ephedrine hydrochloride,and aminophylline(theophylline) were 7～13 ?g?mL-1(r=0.999 9),4.55～8.45 ?g?mL-1(r=0.999 8),and 10.64～19.76 ?g?mL-1(r=0.999 9),respectively,with the average recoveries at 99.35%(RSD=0.97%),100.40%(RSD=1.02%),and 100.57%(RSD=1.08%),respectively.CONCLUSION: The established quality control method could be used for quality control of it.
