Effect of Shuanghuang Tongfeng Capsules on Experimental Gouty Arthritis
- VernacularTitle:双黄痛风胶囊抗痛风性关节炎作用研究
- Author:
Baijia ZHANG
;
Yaou LIU
;
Li HUANG
;
Jia PAN
;
Liu LIU
- Publication Type:Journal Article
- Keywords:
SHTF capsule;
Sodium urate;
Gouty arthritis
- From:
China Pharmacy
2007;0(36):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the effect of Shuanghuang tongfeng capsule(SHTF) on the gouty arthritis.METH-ODS:The gouty arthritis model of rats and rabbits were induced using sodium urate(MSU). The swollen degree of the rat foot,and the amount of synovial fluid,the leucocyte count in synovial fluid and the degree of inflammation of the synovial tissue of joints in rabbits were measured.The effect of SHTF on gouty arthritis was observed. RESULTS:The swollen degree of the foot of rat was lessened obviously by SHTF capsule(5、10、20 g?kg-1,ig).The amount of synovial fluid and the leucocyte count in synovial fluid of the rabbit were decreased significantly by SHTF capsule (4、8、16 g?kg-1,po).The inflammation of the synovial tissue in rabbits was improved obviously by SHTF capsule (8 and 16 g?kg-1,po). CONCLUSION: SHTF capsule have remarkable protective effect on the gouty arthritis induced by sodium urate.
