Pharmacological Effect of Shaducao Oral Succus
- VernacularTitle:刹毒草口服液的药理作用研究
- Author:
Jinying LIU
- Publication Type:Journal Article
- Keywords:
Shaducao oral succus;
Pole-climbing test;
Charcoal clearance test;
Ear-swelling test;
Ink-propelling test
- From:
China Pharmacy
2007;0(36):-
- CountryChina
- Language:Chinese
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Abstract:
OBJECTIVE:To study the pharmacological action of Shaducao oral succus in mice.METHODS:Pole-climbing test,charcoal clearance test,ear-swelling test,ink-propelling test were conducted respectively to observe the antifatigue action of Shaducao oral succus,and its effect on nonspecific immunity,anti-inflammatory and anti-diarrhea effects on mice. RESULTS: Shaducao oral succus markedly prolonged the duration of mice in climbing pole,and it also showed remarkable antifatigue effect. High dose of Shaducao oral succus significantly enhanced mice's charcoal clearance coefficient and clearance capacity index and enhanced mice's immune function.At high,middle and low doses,Shaducao oral succus markedly ameliorated dimethyl benzene-induced otitis,significantly lowered the ink-propelling speed,and satisfactorily relieved diarrhea. CONCLUSION: Shaducao oral succus was proved to be of certain antifatigue,anti-inflammatory and anti-diarrhea effects meanwhile it could enhance the nonspecific immunity of mice.