Stability of the Baicalin in Yanhouyan Mixture
- VernacularTitle:咽喉炎合剂中黄芩苷的稳定性考察
- Author:
Zhuo LI
- Publication Type:Journal Article
- Keywords:
Yanhouyan mixture;
Baicalin;
Classic constant temperature accelerated test method;
Sample observation method;
Stability;
HPLC
- From:
China Pharmacy
2007;0(36):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the stability of Yanhouyan mixture(for pharyngolaryngitis).METHODS: The st-ability of Yanhouyan mixture was investigated by classic constant temperature accelerated test method and sample observation method taking the content of Baicalin as index which was determined by HPLC.RESULTS:The content change of Bacilin in Yanghouyan mixture was in line with the first order kinetics,and the test results for both methods were similar.Under room temperature(25 ℃),the validity duration of Yanhouyan mixture was 1.06 years.CONCLUSION:In establishing the quality standard for Yanhouyan mixture,the advisable storage life of 1 year for which should be considered.