Effect of Pravastatin on Serum Levels of CRP and TNF-? in Patients with Diabetic Nephropathy
- VernacularTitle:普伐他汀对糖尿病肾病患者血清CRP和TNF-?水平的影响研究
- Author:
Fangxuan HAN
;
Hui LIN
;
Ling RU
- Publication Type:Journal Article
- Keywords:
Pravastatin;
CRP;
TNF-?;
Diabetic nephropathy
- From:
China Pharmacy
2007;0(35):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the effects of pravastatin on serum levels of CRP and TNF-? in patients with diabetic nephropathy and study its possible mechanism in the treatment of diabetic nephropathy. METHODS:28 patients with diabetic nephropathy were treated with provastatin plus routine therapy (trial group),another 28 patients with diabetic nephropathy were treated with routine therapy alone (control group). Serum levels of CRP and TNF-? in the two groups were detected after treatment for 24 weeks. RESULTS:The total effect rate in the trial group was 67.9% versus 42.9% in the control group(P
