Analysis of the Use of Antibacterials and Drug Resistance of Common Pathogenic Bacteria Causing Hospital Nosocomial Inflection During the Period 2005～2007
- VernacularTitle:我院2005～2007年抗菌药物使用与常见感染病原菌耐药情况分析
- Author:
Baorong HU
;
Yang MU
;
Qingzhi SHI
- Publication Type:Journal Article
- Keywords:
Antimicrobials;
Pathogenic bacteria;
Drug resistance
- From:
China Pharmacy
2007;0(35):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the use of antibacterials and to evaluate the distribution and drugs resistance of pathogenic bacteria causing hospital nosocomial infection between 2005 and 2007 in our hospital. METHODS:The antibiotic resistance and the data of drug use from 2005 to 2007 in our hospital were analyzed statistically. RESULTS:Over the 3 years,the production rate of ESBLs of Escherichia.coli ascended year by year. The proportion of methicillin resistant staphylococcus aureus (MRSA) in staphylococcus aureus were 79.4%,66.3% and 73.9% respectively over the 3 years. The DDDs of antimicrobials showed an year-on-year increase,with third-generation cephalosporins and fluoroquinolones topping the first two places. CONCLUSION:Antibacterial drugs should be used rationally in clinical practice so as to reduce antibiotic resistance.
