HPLC versus Gravimetric Analysis in the Determination of Sodium New Houttuyfonte Injection
- VernacularTitle:新鱼腥草素钠注射液2种含量测定方法比较
- Author:
Guiying FU
;
Kun WU
;
Yan SUN
- Publication Type:Journal Article
- Keywords:
Sodium new houttuyfonte;
Content determination;
HPLC;
Weighting method
- From:
China Pharmacy
1991;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To compare between the HPLC method and gravimetric analysis in the determination of the content of sodium new Houttuyfonte injection.METHODS:The content of sodium new Houttuyfonte injection was determined by HPLC and gravimetric analysis respectively.HPLC condition: Zorba extent-C18 column(250 mm?4.6 mm,5 ?m) detected by UV(286 nm),and the mobile phase consisted of methanol-water-tetrabutyl ammonium hydroxide(70:30:0.3).The procedure of gravimetric analysis was in line with state drug standard.RESULTS: The determination results were notably different between the two methods.CONCLUSION:Gravimetric analysis showed no specificity in the determination of sodium new Houttuyfonte injection.
