Study on Extraction Technique of Sidiming Capsule
- VernacularTitle:思的明胶囊提取工艺研究
- Author:
Jianchun HUANG
;
Renbin HUANG
;
Zheng YANG
;
Haihua TANG
;
Weizhe JIANG
- Publication Type:Journal Article
- Keywords:
Sidiming capsules;
Orthogonal design;
Extraction technology;
Decoction method;
Alcohol-precipitation meth-od
- From:
China Pharmacy
2007;0(33):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To optimize the extraction technique for Sidiming capsules.METHODS:The technical conditions for the water decoction and the alcohol precipitation were optimized respectively by the orthogonal experiment design L9(34)with hydrosoluble extract used as the index for the water decoction and the catalpol extract for alcohol precipitation.The content of Catalpol was determined by HPLC.RESULTS:The optimum conditions were as follows:decocting the crude drugs twice with 8-fold water,1 h each time.The physic liquor extracted by water was filtered,mixed and concentrated to 1.0 g?mL-1(crude drug),and then precipitated by 75% concentration of alcohol for 24 h.Then the physic liquor was filtered,concentrated and dried by microwave vacuum concentration dryer to obtain the dry ointment.CONCLUSION:The optimum extraction procedure is stable and reliable,and it can be used as the optimal extraction procedure of Sidiming capsules.
