Clinical Study of Shengui Capsule as an Adjunctive Therapy for Severe Congestive Heart Failure
- VernacularTitle:参桂胶囊辅助治疗重度充血性心力衰竭的临床疗效观察
- Author:
Xiushuang GENG
- Publication Type:Journal Article
- Keywords:
Shengui capsule;
Severe congestive heart failure;
Adjunctive therapy;
Clinical efficacy
- From:
China Pharmacy
2007;0(30):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the clinical efficacy and safety of Shengui capsule in treating severe congestive heart failure(CHF).METHODS: 68 patients with severe CHF were randomly divided into 2 groups:34 patients(control group) were treated with routine therapy(rest,oxygen inhalation,inotropic agents and diuretic agents,vasodilators and symptomatic treatment) for 4 weeks,and another 34 patients with routine therapy plus 0.9 g Shengui capsule tid for 4 weeks(trial group).HR,BP,ECG,CD(Color Doppler),ANF(atrial natriuretic peptide),electrolytes and SCr before and after treatment were compared between the two groups.RESULTS: The cardiac function was improved and ANF level was down-regulated in patients treated with Shengui capsule,showing significant difference as compared with control group(P