The in Vitro Antibacterial Activity of the Crude Extract of Total Flavonoids from Lonicera japonica
- VernacularTitle:金银花总黄酮粗提物体外抑菌作用研究
- Author:
Min TANG
;
Yao LIU
;
Yu WANG
;
Di LI
;
Peiyuan XIA
- Publication Type:Journal Article
- Keywords:
Lonicera japonica;
Total flavonoids;
MIC
- From:
China Pharmacy
2007;0(30):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To study the in vitro antibacterial activity of the crude extract of total flavonoids from Lonicera japonica against the main pathogenic bacteria.METHODS: With DM130 macroporous resin as stationary phase,the different components(component A contained more sugar,and content B less sugar;C,D and E components were eluted by 20%,40%,and 60% ethanol,respectively) were obtained by gradient elution of the aqueous extract from Lonicera japonica using different concentration of ethanol,then the MIC of different components on main pathogenic bacteria were detected.RESULTS:The antibacterial activity of component B against staphylococcus aureus was more ponent with its MIC at about 1 mg?mL-1.CONCLUSION:Component B has ponent antibacterial action on main pathogenic bacteria.
