Biliary Aerobic Bacteria Culture and Clinical Application of Antibacterias in 198 Patients Undergoing Acute Cholecystitis Surgery
- VernacularTitle:198例急性胆囊炎手术胆汁需氧菌培养与抗生素选用临床研究
- Author:
Rong HU
- Publication Type:Journal Article
- Keywords:
Biliary bacterial culture;
Acute cholecystitis;
Antibacterias;
Drug sensitivity test
- From:
China Pharmacy
2007;0(29):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the biliary aerobic bacterial infection in acute cholecystitis and their susceptibility to antibacterials.METHODS:Biliary samples of 198 patients undergoing acute cholecystitis surgery in our hospital from 2003 to 2007 were sujected to culture of biliary aerobic bacteria and drug sensitivity test.RESULTS:Of the total 198 bile specimens,147 were postive in aerobic bacteria culture,of which,21 were mixed infection.A total of 225 strains were isolated,with Escherichia coli,Klebsiella pneumonia and Enterobacter representing 42.7%,22.7% and 16.9% respectively.In the drug sensitivity,all the bacteria showed different degree of resistance to antibiotics,with cephalosporines showing the higest antibiotic sensitivity.Gram-positive bacteria were the most sensitive bacteria to vancomycin while Gram-negative bacteria were the most sensitive bacteria to imipenem.CONCLUSION:Biliary bacterial culture and drug sensitivity test are necessary in acute cholecystitis surgery and drugs should be used according to the results of drug sensitivity test.
