Compatible Stability of Isosorbide Mononitrate Injection and Dopamine Hydrochloride Injection
- VernacularTitle:单硝酸异山梨酯注射液与盐酸多巴胺注射液的配伍稳定性考察
- Author:
Pinfang HUANG
;
Changlian WANG
;
Yiwei LIU
- Publication Type:Journal Article
- Keywords:
Dopamine hydrochloride;
Isosorbide mononitrate;
Compatibility stability;
HPLC
- From:
China Pharmacy
2007;0(29):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the compatible stability of isosorbide mononitrate(ISO) and dopamine(DA) hydrochloride in glucose injection.METHODS:The contents of ISO and DA in the mixture of ISO and DA at 20 ℃ and 30 ℃ under natural illumination within 24 h,and the pH and appearance of the mixture were monitored.RESULTS:No significant change was noted in the concentrations of ISO and DA,the pH and the appearance of the mixture at 20 ℃ or 30 ℃.CONCLUSION:The mixture of ISO and DA in glucose injection was stable at 20 ℃ or 30 ℃,but which should be used up within 18 h after mixing.
