Clinical Medication for Infections Caused by ESBLs-producing Escherichia coli and Kalispell Pneumonia
- VernacularTitle:院内产超广谱?-内酰胺酶的大肠埃希菌、肺炎克雷伯菌感染临床用药分析
- Author:
Yufen LUO
;
Weihua LAI
;
Zhaowei GUO
- Publication Type:Journal Article
- Keywords:
Extended spectrum ? lactamases(ESBLs);
Bacterial drug resistance;
Antibiotics;
Escherichia coli;
Kalispell pneumonia1
- From:
China Pharmacy
2007;0(26):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To study the hospital infections caused by ESBLs-producing Escherichia coli and Kalispell.METHODS: Bacterial drug resistance of 460 stains of ESBLs-producing Escherichia coli and Kalispell pneumonia and the application of antibiotics in our hospital in 2005 were analyzed retrospectively.RESULTS: The infections caused by ESBLs-producing Escherichia coli and Kalispell pneumonia were more often found in department of respiratory diseases,ICU and neurosurgery patients,which were treated empirically predominantly with levofloxacin,followed by cefoperazone/sulbactam,but were treated mostly by carbapenems,levofloxacin,cefoperazone/sulbactam after the drug susceptibility test results were obtained.The drug combination was characterized predominantly by combined use of two kinds,at most 6 kinds in combination.CONCLUSION: In most of the cases the medication for infections caused by ESBLs-producing Escherichia coli and Kalispell pneumonia is effective and reasonable.However,in a few cases the application of antibiotics is irrational and nonstandard,which should be given fully attention.
