Study on the Influence of Feiyanning Decoction on Expression of E-cadherin,?-catenin and ?-catenin of Mice with Metastatic Lung Cancer
- VernacularTitle:肺岩宁方对转移性肺癌小鼠上皮标志因子表达的影响
- Author:
Xiaozhen ZHAO
;
Zhenye XU
;
Zhonghua WU
- Publication Type:Journal Article
- Keywords:
Feiyanning Decoction(Decoction for lung cancer);
Epithelial-mesenchymal transition(EMT);
Epithelial symbol factor;
Metastasis of tumors
- From:
Journal of Traditional Chinese Medicine
1992;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the expressions of epithelial symbol factors including E-cadherin,?-catenin,and ?-catenin related to epithelial-mesenchymal transition(EMT) in C57 mice Lewis lung cancer and its mRNA expression affected by Feiyanning Decoction(Decoction for lung cancer).Methods The Real-Time PCR method was adopted to observe the E-cadherin,?-catenin,?-catenin mRNA expression of C57 mice with transplanted tumor in the right armpit and distal metastases and the affection of Feiyanning Decoction on the expression.Results The lung transplanted rate in the Feiyanning group was clearly lower than that in the model group(P
