Research progress of carbon monoxide protection mechanism
- VernacularTitle:一氧化碳保护机制的研究进展
- Author:
Ke MA
;
Xinrong XU
;
Zupeng HU
- Publication Type:Journal Article
- Keywords:
Carbon monoxide;
Heme oxygenase;
Anti-inflammation;
Anti-apoptosis;
Leukocyte adhesion;
Platelet aggregation;
Neurotransmitters
- From:
Chinese Journal of Pathophysiology
1999;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Carbon monoxide(CO) has been considered as a fatal gas.Recent researches show that tissues generate carbon monoxide,and carbon monoxide plays a key role in the tissue physiological and pathological processes.The endogenous CO is generated from the decomposition of heme which is catalyzed by heme oxygenase enzyme(HO).Studies show that CO involves in the process of anti-inflammation,anti-apoptosis,regulation of vascular tone,modulation of leukocyte adhesion and platelet aggregation.CO also functions as neurotransmitters.
