The study of effect of oxamate on the concentration of intracellular calcium in pancreatic cancer cell panc-1
- VernacularTitle:草氨酸盐对人胰腺癌细胞内钙含量影响的研究
- Author:
Shuhua ZHANG
;
Chunyou WANG
;
Jiongxin XIONG
- Publication Type:Journal Article
- Keywords:
Pancreatic Neoplasms;
Oxamate;
Intracellular Calcium
- From:
Chinese Journal of General Surgery
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of oxamate on concentrations of calcium in pancreatic cancer cells.Methods Pancreatic cancer cell panc-1 was cultured in vitro with oxamate for 48 h,then stained with Fluo-3/AM,and the light density of cells for different concentration of oxamate under confocal laser microscopy was observed.Results Oxamate influenced the concentration of calcium in panc-1,and this effect corresponded to the concentration of oxamate.Conclusions Oxamate can induce the increase of the concentration of calcium of panc-1,and then influence the cellular pathophysiologic process.
