Effects of Haikangling Mixture,a Traditional Chinese Medicine on Immunological Function in Immunosuppressed Mice
- VernacularTitle:海康灵合剂对免疫抑制小鼠免疫功能的影响研究
- Author:
Xianghong SUN
;
Huiming WANG
;
Hongling LIU
- Publication Type:Journal Article
- Keywords:
Haikangling Mixture;
Immunological function;
Hemolysin;
Splenic lymphocyte;
Carbon particle clearance
- From:
China Pharmacy
2005;0(24):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To explore the effects of Haikangling Mixture on immunological function in immunosuppressed mice induced by cyclophosphamide. METHODS: Mice were given Haikangling Mixture intragastrically for 14d, and the level of hemolysin was determined by sheep erythrocyte (SRBC) immunization to exploer the influence of Haikangling on humoral immunity in mice; splenic lymphocytes were measured by MTT to observe the influence on cell immunity; the clearance of macrophage were measured by carbon particle clearance method to explore the influence on non-specificity immunity. RESULTS: The level of hemolysin, the cell reproductive activity, splenic lymphocytes and the phagotrophy of mononuclear macrophage were improved obviously by Haikangling Mixture in immunosuppressed mice induced by cyclophosphamide. CONCLUSION: Haikangling Mixture can enhance the immunological function in immunosuppressed mice induced by cyclophosphamide.
