Antiaging Effect of Celery Seed Oil on D-galactose-induced Aging Animal Models
- VernacularTitle:芹菜籽油抗D-半乳糖致衰老模型动物的作用研究
- Author:
Jingbo ZHONG
- Publication Type:Journal Article
- Keywords:
Learning and memory;
Aging models;
Celery seed oil
- From:
China Pharmacy
2005;0(24):-
- CountryChina
- Language:Chinese
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Abstract:
OBJECTIVE:To observe the antiaging effect of celery seed oil (CSO) on aging mice and rats induced by D-galactose. METHODS: Aging models were established with D-galactose hypo. At the same time, the model animals were intragastrically given CSO. After 6 weeks, the effects of CSO on learning and memory were evaluated by step down test and electrophysiological test. And the MDA content, MAO-B and SOD activity in brains of aging mice were measured. RESULTS: CSO can markedly improve the learning and memory of aging mice and rats, reduce the content of MDA and activity of MAO-B, and increase SOD activity. CONCLUSION: CSO has good antiaging effect.
