ADRs Induced by Tetramethylpyrazine:Literature Analysis of 30 Cases
- VernacularTitle:川芎嗪致30例不良反应文献分析
- Author:
Congyan ZENG
;
Quanxi MEI
- Publication Type:Journal Article
- Keywords:
Tetramethylpyrazine(TMP);
ADR;
Literature;
Analysis
- From:
China Pharmacy
2005;0(24):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To explore the general pattern and characteristics of adverse drug reactions (ADRs) induced by Tetramethylpyrazine(TMP) so as to provide references for clinical rational drug use. METHODS: A statistical analysis was conducted on 30 TMP-induced ADR cases reported in domestic medical journals. RESULTS: ADRs of TMP were independent of patient's sex, and which were more often seen in patients aged above 50. The ADRs could occur at any time after medication and involve multiple organs and systems. The clinical manifestations were various and manifested as allergic reaction or even allergic shock in severe cases. CONCLUSION: Doctors and pharmacists should master the pattern and characteristics of ADRs induced by TMP, and strengthen monitoring on the use of TMP to reduce the incidence of ADRs induced by TMP.