Blood Concentration Monitoring of Anti-epileptic Drugs in Our Hospital from 2001 to 2006:Analysis of Monitoring Data
- VernacularTitle:我院2001～2006年抗癫痫药血药浓度监测数据分析
- Author:
Li YANG
;
Zhigang ZHAO
;
Dongmei LI
;
Yueting ZHU
- Publication Type:Journal Article
- Keywords:
Therapeutic drug monitoring;
Anti-epileptic drug;
Sodium valproate;
Carbamazepine;
Phenobarbital;
Phenytoin sodium
- From:
China Pharmacy
2005;0(23):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To discuss the significance of therapeutic drug monitoring(TDM)for rational administration of anti-epileptic drugs and to probe into the cognition of clinic staff on TDM.METHODS:Access database of antiepileptic drugs was established to analyze the TDM data of antiepileptic drugs used from 2001 to 2006.RESULTS:The TDM cases of anti-epileptic drugs increased year by year.The proportions of effective concentration,high blood drug concentration and low blood drug concentration derived from TDM data showed that it is quite necessary to conduct blood drug concentration monitoring.But the lack of individual medication information has hindered the development of patients' individualized medication of anti-epileptic drugs.CONCLUSION:The application of TDM is increasingly widespread;however,the joint efforts of physicians and pharmacists are still needed to ensure individualized medication of anti-epileptic drugs.
