Drug-induced Acute Renal Failure:Analysis of 285 Cases
- VernacularTitle:药物致急性肾功能衰竭285例文献分析
- Author:
Huiyuan WANG
;
Xiaohong CHEN
;
Zhigang ZHAO
- Publication Type:Journal Article
- Keywords:
Drug;
Acute renal failure;
Literature analysis
- From:
China Pharmacy
2005;0(23):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To investigate the clinical feature of drug-induced acute renal failure(ARF).METHODS:285 ARF cases retrieved from CBMdisc and CNKI between Jan.1995 and Dec.2007 were analyzed statistically.RESULTS:Of the 285 drug-induced ARF cases reviewed,186 were male and 99 female.The drugs induced ARF totalled 50 kinds,leading the list in order were mannitol,acyclovir,dopamine,rifampicin,gentamicin,and dextran 40 etc;242(84.91%)received medicine by intravenous drip route.ARF appeared more often from day 1 to 5 after drug use;251 were cured(88.07%),6 took a favorable turn(2.11%),5 discharged from hospital automatically(1.75%),4 developed chronical renal failure(1.40%)and 24 died(8.42%).CONCLUSION:Lots of medicines and common drugs can induce ARF,with incidence rate of drug-induced ARF increased increasingly,however,which has a satisfactory prognosis if with timely and accurate diagnosis and suitable treatment.
