Differentiation of adult canine bone marrow stem cells into neurons.
- Author:
Byung Ho CHOI
1
;
Jin Young HUH
;
Dong Joon PARK
;
Byoung Yong KIM
;
Seoung Ho LEE
;
Sun Young PARK
Author Information
1. Department of Oral & Maxillofacial Surgery, College of Dentistry, Yonsei University, Korea. choibh@wonju.yonsei.ac.kr
- Publication Type:Original Article
- Keywords:
Neuronal differentiation;
Tissue engineering;
Cell culture;
Stem cells
- MeSH:
Adult*;
Bone Marrow*;
Cell Culture Techniques;
Humans;
Iron;
Neurites;
Neurons*;
Stem Cells*;
Tissue Engineering
- From:Journal of the Korean Association of Oral and Maxillofacial Surgeons
2003;29(1):1-4
- CountryRepublic of Korea
- Language:Korean
-
Abstract:
In this study, we showed that neurons could be generated from adult canine bone marrow stem cells by culturing with DMSO/BHA/FeCl2. These neurons differentiated from the bone marrow stem cells formed neurites, expressed neuron-specific markers. This differentiation was enhanced by FeCl2. These results suggest that iron can effectively initiate differentiation of adult bone marrow stem cells into neurons.
