Clinical Efficacy of Dahuang Zhechong Pill on Chronic Hepatitis with Hepatic Fibrosis
- VernacularTitle:大黄蜇虫丸治疗慢性肝炎肝纤维化的临床疗效观察
- Author:
Wenli LI
;
Shipin WU
- Publication Type:Journal Article
- Keywords:
Chronic hepatitis;
Hepatic fibrosis;
Dahuang zhechong pill;
Clinical efficacy
- From:
China Pharmacy
2005;0(21):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the clinical effect of Dahuang zhechong pill on chronic hepatitis with hepatic fibrosis.METHODS:A total of 128 patients with chronic hepatitis with hepatic fibrosis were randomly divided into treatment group(68 cases) and control group(60 cases).The control group received routine hepatic protective therapy,while the treatment group received routine hepatic protective therapy and Dahuang zhechong pills(6 g?d-1) concomitantly.The course of treatment lasted for 6 months.The clinical symptoms,liver function,hyaluronic acid(HA),pro-collagen Ⅲ(PC Ⅲ),cholyglycine(CG) and collagen type Ⅳ(ⅣC),and ultrasound image were observed in both groups.RESULTS:Levels of serum HA,PCⅢ,CG,and ⅣC decreased significantly in treatment group,and the difference between two groups was significant(P
