Effect of Danhong Injection on Endothelial Function in Patients with Coronary Heart Disease
- VernacularTitle:丹红注射液对冠心病患者血管内皮功能影响的临床研究
- Author:
Ru ZHANG
;
Qiaofeng SONG
;
Xizhu WANG
- Publication Type:Journal Article
- Keywords:
Danhong injection;
Sterile Danshen injection powder;
NO;
vWF;
FMD
- From:
China Pharmacy
2005;0(21):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the efffect of Danhong injection on the endothelial function in patients with stable coronary heart disease(CHD).METHODS:In this randomized control study,82 CHD cases were randomly assigned to receive Danhong injection or Sterile Danshen injection powder by iv gtt.The endothelial function and the inflammation-related indexes in two groups were compared after 2-week treatment.RESULTS:As compared with before treatment,in Danhong group,the levels of NO and flow-mediated dilatation(FMD) were significantly up-regulated while the levels of vWF and CRP(C-reaction protein) were significantly down-regulated after treatment;however,no significant difference was noted in Sterile Danshen injection powder group in endothelial function and the inflammation-related indexes.There were significant differences between the two groups(P
