Curative Effects of Chailing Decoction Granules Prepared by Different Preparation Technology for Chronic Renal Failure in Rats
- VernacularTitle:制备工艺对柴苓汤颗粒抗大鼠慢性肾功能衰竭的影响研究
- Author:
Jianfeng WU
;
Xuxin ZENG
;
Haitao ZHAN
;
Yingshi LIU
- Publication Type:Journal Article
- Keywords:
Chailing decoction granule;
Chronic renal failure;
Preparation technology;
Effect
- From:
China Pharmacy
2005;0(21):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the curative effect of different Chailing decoction granules on chronic renal failure(CRF) in rats.METHODS:SD rats in trial groups and model group were given adenine to induce CRF model.The trial groups were treated with Japanese Tsumura granules,imitating Japanese method granules or Chinese normal method granule.The model group and the control group were treated with saline.The urine,blood biochemical parameters as well as morphological change of kidney were monitored.RESULTS:Compared with model group,Japanese Tsumura granules and imitating Japanese method granules significantly reduced the levels of blood ureanitrogen,serum total protein,serum cholesterol and urinary protein,and the damage on renal interstitium was lessened significantly(P
