Effect of Bushen Yiqi Hexue Recipe on the Endometrial Gland Apoptosis in Blastocyst Implantation Dysfunctional Mice
- VernacularTitle:补肾益气和血方对胚泡着床障碍小鼠子宫内膜腺体凋亡的影响
- Author:
Dongmei HUANG
;
Guangying HUANG
;
Fuer LU
- Publication Type:Journal Article
- Keywords:
Blastocyst implantation dysfunction;
Apoptosis;
Proliferating cell nuclear antigen(PCNA);
bax;
bcl-2;
Caspase-3;
Bushen Yiqi Hexue Recipe(Recipe to reinforce kidney,replenish qi and harmonize blood)
- From:
Journal of Traditional Chinese Medicine
1993;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the effect of Bushen Yiqi Hexue Recipe(Recipe to reinforce kidney,replenish qi and harmonize blood)on the endometrial gland apoptosis in blastocyst implantation dysfunctional mice.Methods The mice models of blastocyst implantation dysfunction were made and divided into control,model and treated groups with 30 in each.Pregnancy rate,number of implantation blastocysts,the expression of proliferating cell nuclear antigen(PCNA),bax,bcl-2 and activated Caspase-3 were observed.Results Compared with the control group,pregnancy rate and mean implanted blastocysts in the model group were remarkably reduced.Compared with the model group,pregnancy rate and mean implanted blastocysts in the treated group were significantly improved(P
