The expression and biological significance of HLJ1 in hepatocellular carcinoma tissue
- VernacularTitle:HLJ1基因在肝细胞癌组织中的表达及其生物学意义
- Author:
Haijun LIU
;
Zhiming WANG
;
Nengzhi CHEN
- Publication Type:Journal Article
- Keywords:
Carcinoma,Hepatocellular;
Genes,HLJ1;
Neoplasm Recurrence;
Neoplasm Metastasis
- From:
Chinese Journal of General Surgery
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To analyze the expression of HLJ1 in the tissues of hepatocellular carcinoma(HCC) and the correlation between its expression and clinical pathological characteristic.Methods HLJ1 mRNA expression level was determined in 32 HCC tissues and their associated noncancerous liver tissues by reverse transcription polymerase chain reaction(RT-PCR).The correlation of HLJ1 expression level with clinicopathologic variables was also analyzed.Results HLJ1 mRNA expression level was significantly lower in HCC than in associated noncancerous liver tissue [(1.18?0.82) vs.(1.92?1.15),P